at the lab:

Graduate Students

Highly motivated undergraduate students are encouraged to apply to the PhD program at the University of North Carolina at Chapel Hill. Interested students may contact Prof. You via email.

Chem PhD Program Info  |  UNC Chem Department

Post Docs

The You Lab at UNC Chapel Hill has a consistent interest in pursuing functional materials, from fundamentals to applications (please refer to research for more details). We always welcome talented PhDs to join our team to further pursue your research interest/career. While we are currently recruiting candidates to fulfill the below position(s), any candidate might contact Prof. You via email to indicate the research interest and proposed research directions/projects.

Polymer-protein/antibody conjugation for novel therapeutics

The candidate will utilize biochemical, biophysical, and cellular assays, and develop new technologies to explore novel polymer-protein/antibody as therapeutics for different diseases. Strong and ready candidate will have the opportunity to join a startup company co-founded by Prof. You based on patented technologies.


  • Lead the polymer – protein/antibody conjugation project focusing on polymer-protein conjugation & purification, as well as analytical, biochemical, and cellular assays.
  • Lead the drug discovery work on differentiated lead molecules including but not limited to antibodies, multi-specifics, cytokines, fusion proteins, and proteases.
  • Maintaining research stage instruments such as Akta protein purification system, HPLC, incubator, etc.
  • Responsible for developing new technologies and platforms to stay at the cutting edge of polymer-drug conjugates.


  • Ph.D. and postdoctoral work in Biochemistry, Molecular & Cell Biology or related fields.
  • Knowledge and experience applying a variety of bioconjugation techniques.
  • Expertise in biology, immunology, and biochemistry to design and implement functional and cell-based assays to support technology development, polymer-protein/antibody lead candidate selections, and mechanistic studies is preferred.
  • Experience in engineering and characterization of protein and antibody variants.
  • Experience and knowledge of molecular biology, protein expression in bacterial, yeast and mammalian cells, purification and characterization.
  • Ability and willingness to learn rapidly, and participate in multidisciplinary collaborations with internal and external teams.
  • Excellent written, oral, and organizational skills.

Contact us:

Interested candidates for the direction above can send the cover letter, CV, and names of references to Prof. Wei You at wyou@unc.edu.